SCHEMBL8097138

SCHEMBL8097138

CCCC(c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.40
GSR P00390 1/20 0.40
NPC1 O15118 2/20 0.38
ADAM17 P78536 1/20 0.38
MAPT P10636 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
LMNA P02545 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 2/20 0.35
MEN1 O00255 1/20 0.35
HTR2A P28223 2/20 0.34
HRH1 P35367 2/20 0.34
SIGMAR1 Q99720 1/20 0.34
MAPK1 P28482 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
CNR1 P21554 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8089501 0.89 POLB (0.43) GSRNPC1ADAM17NPSR1LMNA
SCHEMBL11743451 0.86 NAAA (0.41) NPSR1KMT2AALDH1A1POLBMEN1
SCHEMBL266714 0.84 LMNA (0.43) GSRNPC1ADAM17MAPTNPSR1
SCHEMBL7996196 0.81 GSR (0.38) GSRNPC1ADAM17MAPTNPSR1
SCHEMBL10785465 0.81 TDP1 (0.44) TDP1ALDH1A1SMN1; SMN2
SCHEMBL20592078 0.81 HRH1 (0.52) GSRNPC1ADAM17MAPTNPSR1
SCHEMBL1231748 0.81 GSR (0.40) GSRNPC1ADAM17MAPTNPSR1
SCHEMBL9641202 0.81 NPC1 (0.41) GSRNPC1ADAM17MAPTNPSR1
SCHEMBL11130514 0.81 GSR (0.47) GSRNPC1ADAM17MAPTNPSR1
SCHEMBL1286813 0.81 GSR (0.40) GSRNPC1ADAM17MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023156832-A1 A PROCESS FOR PREPARATION OF HIGHLY PURE 4-(N-BUTYL) ANILINE VINATI ORGANICS LIMITED (IN) 2023-08-24 WO disclosed
EP-1053990-A2 A method of producing an aromatic ketone and an aromatic ketone composition containing it TORAY INDUSTRIES, INC. (JP) 2000-11-22 EP disclosed