Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105709 | 0.90 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL8099734 | 0.86 | BDKRB2 (0.54) | BDKRB2 | |
| SCHEMBL8099285 | 0.85 | BDKRB2 (0.70) | BDKRB2 | |
| SCHEMBL8089811 | 0.83 | BDKRB2 (0.61) | BDKRB2 | |
| SCHEMBL8098948 | 0.83 | BDKRB2 (0.61) | BDKRB2 | |
| SCHEMBL8098918 | 0.83 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL8803792 | 0.81 | BDKRB2 (0.75) | BDKRB2 | |
| SCHEMBL8090589 | 0.81 | BDKRB2 (0.59) | BDKRB2 | |
| SCHEMBL8803785 | 0.81 | BDKRB2 (0.75) | BDKRB2 | |
| SCHEMBL7743013 | 0.80 | BDKRB2 (0.77) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795547-B1 | (Aminoalkyl- and acylaminoalkyl-oxy)benzyloxyquinolines, process for their preparation and use as Bradykinin receptor antagonists | HOECHST AG (DE) | 2000-05-10 | — | — | EP | claimed |
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |