Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 16/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173952 | 0.91 | BDKRB2 (0.63) | BDKRB2MEN1KMT2A | |
| SCHEMBL8367630 | 0.85 | BDKRB2 (0.62) | BDKRB2MEN1KMT2A | |
| SCHEMBL8174118 | 0.85 | BDKRB2 (0.58) | BDKRB2MEN1KMT2A | |
| SCHEMBL8169517 | 0.84 | BDKRB2 (0.42) | BDKRB2 | |
| SCHEMBL8169656 | 0.84 | BDKRB2 (0.41) | BDKRB2 | |
| SCHEMBL6936587 | 0.84 | BDKRB2 (0.66) | BDKRB2MEN1KMT2A | |
| SCHEMBL8175081 | 0.83 | BDKRB2 (0.56) | BDKRB2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6644122 | 0.83 | BDKRB2 (0.65) | BDKRB2MEN1KMT2A | |
| SCHEMBL8097169 | 0.83 | BDKRB2 (0.60) | BDKRB2 | |
| SCHEMBL8364184 | 0.82 | BDKRB2 (0.67) | BDKRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140341-A | FOR TREATING PAIN | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-10-31 | — | — | US | claimed |
| EP-0795547-B1 | (Aminoalkyl- and acylaminoalkyl-oxy)benzyloxyquinolines, process for their preparation and use as Bradykinin receptor antagonists | HOECHST AG (DE) | 2000-05-10 | — | — | EP | claimed |
| JP-10001472-A | — | — | None | — | — | JP | disclosed |
| US-6140341-A | FOR TREATING PAIN | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-10-31 | — | — | US | disclosed |
| EP-0795547-B1 | (Aminoalkyl- and acylaminoalkyl-oxy)benzyloxyquinolines, process for their preparation and use as Bradykinin receptor antagonists | HOECHST AG (DE) | 2000-05-10 | — | — | EP | disclosed |
| US-5994368-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| JP-H101472-A | AMINOALKYL AND ACYLAMINOALKYL ETHERS, THEIR PRODUCTION AND THEIR USE AS BRADYKININ RECEPTOR ANTAGONIST | HOECHST AG | 1998-01-06 | — | — | JP | disclosed |
| EP-0807105-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |
| EP-0795547-A1 | (Aminoalkyl- and acylaminoalkyl-oxy)benzyloxyquinolines, process for their preparation and use as Bradykinin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |