SCHEMBL8097304

SCHEMBL8097304

CC(C)N(CCOC(=O)C1(c2ccccc2)CCCCC1)C(C)C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.69
PRCP P42785 3/20 0.69
ALDH1A1 P00352 5/20 0.67
POLB P06746 1/20 0.67
CHRM2 P08172 2/20 0.62
CHRM1 P11229 2/20 0.62
HTT P42858 2/20 0.60
LMNA P02545 2/20 0.60
TSHR P16473 2/20 0.60
CYP1A2 P05177 2/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2D6 P10635 2/20 0.60
TMEM97 Q5BJF2 2/20 0.60
KDM4E B2RXH2 1/20 0.60
SLC22A1 O15245 1/20 0.60
THRB P10828 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
APOBEC3A P31941 3/20 0.60
APOBEC3G Q9HC16 3/20 0.60
MAPK1 P28482 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8105106 0.99 ALDH1A1 (0.70) SIGMAR1PRCPALDH1A1POLBCHRM2
SCHEMBL8110535 0.99 SIGMAR1 (0.70) SIGMAR1PRCPALDH1A1POLBCHRM2
Hydrochloric Acid SCHEMBL8112521 0.97 ALDH1A1 (0.71) SIGMAR1PRCPALDH1A1POLBCHRM2
SCHEMBL8319974 0.96 SIGMAR1 (0.67) SIGMAR1PRCPALDH1A1POLBCHRM2
Hydrochloric Acid SCHEMBL8317910 0.95 ALDH1A1 (0.65) SIGMAR1PRCPALDH1A1POLBCHRM2
Hydrochloric Acid SCHEMBL8106500 0.95 ALDH1A1 (0.67) SIGMAR1PRCPALDH1A1POLBCHRM2
Hydrochloric Acid SCHEMBL8097297 0.88 ALDH1A1 (0.58) SIGMAR1PRCPALDH1A1POLBCHRM2
SCHEMBL8107178 0.86 PRCP (0.55) SIGMAR1PRCPALDH1A1POLBCHRM2
Hydrochloric Acid SCHEMBL8106528 0.86 ALDH1A1 (0.57) SIGMAR1PRCPALDH1A1POLBCHRM2
Hydrochloric Acid SCHEMBL8105154 0.86 ALDH1A1 (0.57) SIGMAR1PRCPALDH1A1POLBCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0923536-A1 ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION Pharmacia & Upjohn Aktiebolag (SE) 1999-06-23 EP claimed
WO-1998004517-A1 ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION PHARMACIA & UPJOHN AB (SE) 1998-02-05 WO claimed
US-6124354-A TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME PHARMACIA & UPJOHN AB (SE) 2000-09-26 US disclosed
EP-0923536-A1 ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION Pharmacia & Upjohn Aktiebolag (SE) 1999-06-23 EP disclosed
WO-1998004517-A1 ARYLCYCLOALKANE CARBOXYLIC ESTERS, THEIR USE, PHARMACEUTICAL COMPOSITIONS AND PREPARATION PHARMACIA & UPJOHN AB (SE) 1998-02-05 WO disclosed