Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14647018 | 0.71 | F7 (0.39) | MTNR1BFFAR1LTA4HNPC1RAB9A | |
| SCHEMBL860262 | 0.66 | F7 (0.41) | NPC1POLBRAB9A | |
| SCHEMBL860435 | 0.65 | F7 (0.51) | — | |
| SCHEMBL840797 | 0.64 | FFAR1 (0.40) | FFAR1MEN1POLBRAB9AKMT2A | |
| SCHEMBL840788 | 0.63 | F7 (0.42) | — | |
| SCHEMBL24075754 | 0.61 | RNF4 (0.69) | MTNR1BFFAR1MTNR1ANPC1POLB | |
| SCHEMBL13452875 | 0.60 | ALDH1A1 (0.66) | LTA4HMEN1NPC1RAB9AKMT2A | |
| SCHEMBL710331 | 0.59 | MAPT (0.59) | MEN1NPC1RAB9AKMT2AHTT | |
| SCHEMBL10061571 | 0.58 | USP2 (0.68) | MTNR1BMTNR1AMEN1NPC1RAB9A | |
| SCHEMBL2174618 | 0.57 | ALDH1A1 (0.47) | MTNR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007015-A1 | MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY | SANOFI-AVENTIS (FR) | 2009-01-15 | — | — | WO | disclosed |