Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104825 | 0.79 | OPRM1 (0.45) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL13163320 | 0.74 | OPRM1 (0.41) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL432561 | 0.73 | OPRM1 (0.59) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL6891511 | 0.70 | OPRM1 (0.69) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL872608 | 0.70 | OPRM1 (0.56) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL7355415 | 0.70 | OPRM1 (0.51) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL56575 | 0.70 | NPC1 (0.57) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL8107113 | 0.69 | OPRL1 (0.46) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL181145 | 0.68 | NPC1 (0.55) | OPRM1OPRD1OPRL1CA12CA1 | |
| SCHEMBL19249603 | 0.68 | NPC1 (0.55) | OPRM1OPRD1OPRL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |