Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768887 | 0.98 | NPC1 (0.55) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL19249603 | 0.98 | NPC1 (0.55) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL181145 | 0.98 | NPC1 (0.55) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL872608 | 0.95 | OPRM1 (0.56) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| Ethylene SCHEMBL11706079 | 0.94 | NPC1 (0.53) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL432561 | 0.91 | OPRM1 (0.59) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3520928 | 0.86 | NPC1 (0.54) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL624811 | 0.84 | NPC1 (0.51) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| Acrylic Acid SCHEMBL212480 | 0.83 | ALDH1A1 (0.55) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3281976 | 0.83 | OPRM1 (0.53) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | claimed |
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | disclosed |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO HEALTH, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO HEALTH, INC. | 2023-11-02 | — | — | US | disclosed |
| US-11673857-B2 | Preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile | Zhejiang Rongyao Biotech CO., LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| US-11673857-B2 | Preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile | Zhejiang Rongyao Biotech CO., LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | disclosed |
| EP-3362445-B1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2023-01-25 | — | — | EP | disclosed |
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| WO-1995000483-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1995-01-05 | — | — | WO | disclosed |
| US-5281714-A | Enzyme inhibitors or antioxidants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |
| US-5223530-A | Selective high-affinity ligands for treatment of psychological disorders, side effect reduction | SRI, INTERNATIONAL (US) | 1993-06-29 | — | — | US | disclosed |
| US-5179216-A | Anticholesterol agents and atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| EP-0495084-A1 | ARYLCYCLOALKANEPOLYALKYLAMINES | SRI INTERNATIONAL (US) | 1992-07-22 | — | — | EP | disclosed |
| WO-1992002481-A1 | ARYLCYCLOALKANEPOLYALKYLAMINES | SRI INTERNATIONAL (US) | 1992-02-20 | — | — | WO | disclosed |
| EP-0471493-A1 | N,N',N'-trisubstituted-5-bisaminomethylene-1,3-dioxane-4,6-dione inhibitors of acyl-CoA:cholesterol-acyl transferase | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-02-19 | — | — | EP | disclosed |
| US-5086054-A | Selective high-affinity ligands to sigma boding sites, administering, amipsychotic, antiarrhythmia, antiischemic agents anticonvulsants, reduced side effects | SRI INTERNATIONAL (US) | 1992-02-04 | — | — | US | disclosed |
| US-4684396-A | Triazole and imidazole compounds useful as plant growth regulators and fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-08-04 | — | — | US | disclosed |
| EP-0153797-A1 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NNT | NPC1 161/4885ALDH1A1 984/4885RAB9A 1657/4885 |
| US-11547701-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NQO1 | NPC1 174/4885ALDH1A1 994/4885RAB9A 1917/4885 |
| US-11673857-B2 | Preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile | CPNE4, CPN1, DCUN1D4 | NPC1 362/4885ALDH1A1 442/4885RAB9A 3108/4885 |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | NPC1 123/4885ALDH1A1 1273/4885RAB9A 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.