Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419291 | 0.82 | PDE10A (0.49) | PDE10ACYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL5717569 | 0.81 | LTB4R (0.48) | PDE10ACYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL2182496 | 0.79 | PDE10A (0.47) | PDE10ACYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL5717525 | 0.78 | PDE10A (0.46) | PDE10ACYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL2412735 | 0.77 | RECQL (0.50) | PDE10ACYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4418553 | 0.76 | ALDH1A1 (0.59) | CYP2E1CYP3A4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL2411486 | 0.76 | RECQL (0.48) | PDE10ACYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL4430505 | 0.75 | TSHR (0.52) | KDM4E | |
| SCHEMBL2841442 | 0.75 | PDE10A (0.46) | PDE10ACYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL15453838 | 0.75 | NR4A2 (0.43) | PDE10ACYP2E1CYP3A4CYP2A6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117940-A | SOLID PHASE SYNTHESIS OF COMPOUNDS SUCH AS THE IMIDAZOLES, BENZODIAZEPINES, PYRAZINES, AND STEROID MIMICS. | ADVANCED SYNTECH, LLC, A KENTUCKY LIMITED LIABILITY CORPORATION | 2000-09-12 | — | — | US | disclosed |