Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.42 |
| ▸ | FNTB | P49356 | 3/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 3/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097236 | 0.88 | CCR5 (0.44) | FNTAFNTBPGGT1BCCR5GPBAR1 | |
| SCHEMBL8098226 | 0.85 | FNTA (0.45) | FNTAFNTBPGGT1BCCR5ALOX12 | |
| SCHEMBL8097422 | 0.85 | GPBAR1 (0.49) | FNTAFNTBPGGT1BGPBAR1ALDH1A1 | |
| SCHEMBL8434674 | 0.85 | GPBAR1 (0.49) | FNTAFNTBPGGT1BGPBAR1ALDH1A1 | |
| SCHEMBL8097915 | 0.80 | FNTA (0.45) | FNTAFNTBPGGT1BCCR5ALOX12 | |
| SCHEMBL7453431 | 0.74 | FNTA (0.44) | FNTAFNTBPGGT1BCCR5EP300 | |
| SCHEMBL7521521 | 0.74 | FNTA (0.44) | FNTAFNTBPGGT1BCCR5EP300 | |
| SCHEMBL8427986 | 0.73 | FNTA (0.53) | FNTAFNTBPGGT1BGPBAR1KCNH2 | |
| SCHEMBL8098229 | 0.73 | FNTA (0.53) | FNTAFNTBPGGT1BGPBAR1KCNH2 | |
| SCHEMBL446560 | 0.73 | FNTA (0.45) | FNTAFNTBPGGT1BCCR5ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |