Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862283 | 0.79 | KDM4E (0.44) | HSD11B1ALDH1A1KDM4EHTT | |
| SCHEMBL3510746 | 0.78 | ALDH1A1 (0.40) | HSD11B1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL2812495 | 0.76 | ALDH1A1 (0.39) | HSD11B1ALDH1A1POLBKDM4EHTT | |
| SCHEMBL6491717 | 0.75 | ALDH1A1 (0.38) | HSD11B1ALDH1A1POLBKDM4EHTT | |
| SCHEMBL30477996 | 0.75 | HSD11B1 (0.46) | HSD11B1ALDH1A1POLBKDM4EHTT | |
| SCHEMBL26217994 | 0.75 | ALDH1A1 (0.38) | HSD11B1ALDH1A1POLBKDM4EHTT | |
| Adamantaneacetic Acid SCHEMBL24688608 | 0.75 | ALDH1A1 (0.62) | HSD11B1ALDH1A1POLBMEN1KMT2A | |
| Adamantaneacetic Acid SCHEMBL306081 | 0.75 | ALDH1A1 (0.62) | HSD11B1ALDH1A1POLBMEN1KMT2A | |
| Adamantaneacetic Acid SCHEMBL6865701 | 0.75 | ALDH1A1 (0.62) | HSD11B1ALDH1A1POLBMEN1KMT2A | |
| Adamantaneacetic Acid SCHEMBL4147939 | 0.73 | ALDH1A1 (0.60) | HSD11B1ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661271-B1 | AZEPINE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS SIGMA-RECEPTOR LIGANDS | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0661271-A1 | AZEPINE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-07-05 | — | — | EP | disclosed |