Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 18/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8097228 | 0.99 | ABCB11 (0.66) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL8095472 | 0.89 | ABCB11 (0.84) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL8331948 | 0.89 | ABCB11 (0.59) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL8088900 | 0.88 | ABCB11 (0.82) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL8088395 | 0.85 | ABCB11 (0.67) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL8095333 | 0.85 | ABCB11 (0.66) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL8088537 | 0.85 | ABCB11 (0.64) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL8127850 | 0.85 | ABCB11 (0.64) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL8097213 | 0.84 | ABCB11 (0.63) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL265361 | 0.83 | ABCB11 (0.71) | ABCB11ADRB2ADRB1DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850232-B1 | BENZOTHIAZOLONE DERIVATIVES | ASTRA PHARMA PROD (GB) | 2000-03-15 | — | — | EP | claimed |
| US-6080869-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-06-27 | — | — | US | disclosed |
| EP-0850232-B1 | BENZOTHIAZOLONE DERIVATIVES | ASTRA PHARMA PROD (GB) | 2000-03-15 | — | — | EP | disclosed |
| US-6008365-A | ADRENORECEPTOR AGONISTS AND DOPAMINE DA2-RECEPTOR AGONISTS, USEFUL IN THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-12-28 | — | — | US | disclosed |
| US-5977384-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| US-5973167-A | Intermediates for making benzothiazolone derivatives | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-10-26 | — | — | US | disclosed |
| US-5846989-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-12-08 | — | — | US | disclosed |