Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 1.00 |
| ▸ | FNTB | P49356 | 14/20 | 1.00 |
| ▸ | PGGT1B | P53609 | 9/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097474 | 0.81 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL8586902 | 0.81 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL8106918 | 0.76 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL8869530 | 0.74 | FNTA (0.63) | FNTAFNTBPGGT1B | |
| SCHEMBL8868864 | 0.73 | FNTA (0.69) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL8868606 | 0.73 | FNTA (0.62) | FNTAFNTBPGGT1B | |
| SCHEMBL629747 | 0.73 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL15331422 | 0.73 | FNTA (0.57) | FNTAFNTBPGGT1B | |
| SCHEMBL4171948 | 0.72 | CYP2C8 (0.69) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL8934722 | 0.72 | FNTA (0.62) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011175-A | Inhibition of farnesyltransferase | UNIVERSITY OF PITTSBURGH (US) | 2000-01-04 | — | — | US | disclosed |
| US-5965539-A | PEPTIDOMIMETICS; ANTI-CANCER DRUGS | UNIVERISTY OF PITTSBURGH (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | disclosed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | disclosed |