Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 1.00 |
| ▸ | FNTB | P49356 | 11/20 | 1.00 |
| ▸ | PGGT1B | P53609 | 7/20 | 1.00 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 2/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586902 | 0.86 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL8097474 | 0.86 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL8107197 | 0.78 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL68931 | 0.77 | CA12 (0.69) | FNTAFNTBPGGT1BCA12CA1 | |
| SCHEMBL8112651 | 0.76 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL8097487 | 0.76 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL27715902 | 0.76 | CA12 (0.71) | FNTAFNTBPGGT1BCA12CA1 | |
| SCHEMBL8097476 | 0.75 | FNTA (1.00) | FNTAFNTBPGGT1B | |
| SCHEMBL67941 | 0.74 | CA12 (0.68) | FNTAFNTBPGGT1BCA12CA1 | |
| SCHEMBL2569067 | 0.74 | LOXL2 (0.71) | FNTAFNTBPGGT1BCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011175-A | Inhibition of farnesyltransferase | UNIVERSITY OF PITTSBURGH (US) | 2000-01-04 | — | — | US | disclosed |
| US-5965539-A | PEPTIDOMIMETICS; ANTI-CANCER DRUGS | UNIVERISTY OF PITTSBURGH (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | disclosed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | disclosed |