SCHEMBL8586902

SCHEMBL8586902

NC(CS)CNc1ccc(-c2cccc(C(=O)O)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 12/20 1.00
FNTB P49356 12/20 1.00
PGGT1B P53609 7/20 1.00
ANPEP P15144 1/20 0.52
ENPEP Q07075 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8097474 1.00 FNTA (1.00) FNTAFNTBPGGT1BANPEPENPEP
SCHEMBL8106918 0.86 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL8097476 0.86 FNTA (1.00) FNTAFNTBPGGT1BANPEPENPEP
SCHEMBL8112651 0.82 FNTA (1.00) FNTAFNTBPGGT1BANPEP
SCHEMBL8868864 0.81 FNTA (0.69) FNTAFNTBPGGT1B
SCHEMBL8097487 0.81 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL8105313 0.80 FNTA (1.00) FNTAFNTBPGGT1BANPEPENPEP
SCHEMBL8107197 0.79 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL8106726 0.79 FNTA (1.00) FNTAFNTBPGGT1BANPEPENPEP
SCHEMBL8869530 0.78 FNTA (0.63) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998043629-A1 ANTI-INFLAMMATORY MEDICAMENT CONTAINING FARNESYL PROTEIN TRANSFERASE INHIBITOR, ITS PREPARATION AND USE FERRING B.V. (NL) 1998-10-08 WO claimed
WO-1998043629-A1 ANTI-INFLAMMATORY MEDICAMENT CONTAINING FARNESYL PROTEIN TRANSFERASE INHIBITOR, ITS PREPARATION AND USE FERRING B.V. (NL) 1998-10-08 WO disclosed