Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 10/20 | 0.36 |
| ▸ | PPARA | Q07869 | 10/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111202 | 0.85 | KDM4E (0.37) | CYP3A4CYP11B1CYP11B2KDM4ETSHR | |
| SCHEMBL8097528 | 0.83 | MAPT (0.41) | PPARDPPARAMAPTKDM4EHTT | |
| SCHEMBL8097580 | 0.82 | MAPT (0.41) | PPARDPPARAMAPTKDM4EHTT | |
| SCHEMBL8097530 | 0.80 | CYP3A4 (0.38) | ABCB11CYP17A1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL8097526 | 0.80 | CYP3A4 (0.38) | ABCB11CYP17A1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL8106768 | 0.80 | CYP3A4 (0.37) | ABCB11CYP17A1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL8106771 | 0.80 | CYP3A4 (0.37) | ABCB11CYP17A1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL8718644 | 0.78 | CYP3A4 (0.43) | ABCB11CYP17A1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL8718648 | 0.78 | CYP3A4 (0.43) | ABCB11CYP17A1CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL8111174 | 0.77 | CYP3A4 (0.35) | ABCB11CYP17A1CYP3A4CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033367-A2 | Process for the preparation of optically active triazole derivatives and their imidazolidin-2-one intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5677464-A | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0687672-A2 | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |