Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534425 | 0.92 | CTSK (0.57) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL10534413 | 0.88 | CTSK (0.53) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL10537886 | 0.87 | CYP1A2 (0.54) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL9692057 | 0.86 | CTSK (0.61) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL10535044 | 0.86 | CTSK (0.61) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL4751261 | 0.85 | CTSL (0.48) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL22542469 | 0.84 | CTSK (0.50) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL17710296 | 0.84 | CTSK (0.54) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL11023873 | 0.84 | CTSK (0.58) | CTSKCTSLCTSSCTSBCAPN1 | |
| SCHEMBL22757739 | 0.84 | CTSK (0.58) | CTSKCTSLCTSSCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151306-A1 | SYNTHESIS OF CYCLODEPSIPEPTIDE COMPOUNDS HAVING ANTINEOPLASTIC AND/OR ANTIMICROBIAL ACTIVITY | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |
| US-4755592-A | Statine-containing peptides useful in medicaments | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-07-05 | — | — | US | disclosed |
| US-4746649-A | Diamino acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1988-05-24 | — | — | US | disclosed |
| EP-0198271-A2 | Peptides | MERCK PATENT GmbH (DE) | 1986-10-22 | — | — | EP | disclosed |