Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808897 | 0.78 | GID4 (0.55) | CETPUSP2MAPTKDM4EALDH1A1 | |
| SCHEMBL30427144 | 0.78 | CETP (0.52) | CETPPIN1KMT2AMEN1MAPT | |
| SCHEMBL28999657 | 0.78 | CETP (0.52) | CETPPIN1KMT2AMEN1MAPT | |
| SCHEMBL9797951 | 0.78 | CETP (0.43) | CETPPIN1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9797956 | 0.78 | CETP (0.43) | CETPPIN1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9438607 | 0.75 | GID4 (0.58) | KMT2AMEN1MAPTHTR2AHTR2C | |
| SCHEMBL1722733 | 0.74 | GAA (0.51) | MAPTHTR2AHTR2BGAAHPGD | |
| SCHEMBL3976186 | 0.73 | CHRNA7 (0.43) | CETPPIN1HTR2AKDM4EALDH1A1 | |
| SCHEMBL16340316 | 0.72 | PRCP (0.51) | KMT2AMEN1MAPTHTR2AKDM4E | |
| SCHEMBL11223423 | 0.71 | MEN1 (0.51) | KMT2AMEN1USP2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955992-B1 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORP (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1955992-A2 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-13 | — | — | EP | disclosed |