Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293862 | 0.85 | CA1 (0.49) | MAPTHPGDNPC1TP53MAOA | |
| SCHEMBL9438607 | 0.84 | GID4 (0.58) | GID4MAPTNPC1ALDH1A1HDAC1 | |
| SCHEMBL16340316 | 0.83 | PRCP (0.51) | MAPTHPGDNPC1TP53ALDH1A1 | |
| SCHEMBL809758 | 0.82 | CA1 (0.55) | GID4DRD1 | |
| SCHEMBL1722733 | 0.82 | GAA (0.51) | MAPTHPGDTP53CYP1A2LMNA | |
| SCHEMBL14267920 | 0.78 | CA1 (0.56) | KDM4E | |
| SCHEMBL809757 | 0.78 | CETP (0.51) | MAPTHPGDALDH1A1KDM4ECASP1 | |
| SCHEMBL9797951 | 0.78 | CETP (0.43) | GID4RAB9ANPBWR1CYP2D6CETP | |
| SCHEMBL9797956 | 0.78 | CETP (0.43) | GID4RAB9ANPBWR1CYP2D6CETP | |
| SCHEMBL6826748 | 0.77 | SLC6A2 (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467202-B1 | METHODS FOR SELECTIVELY SYNTHESIZING 1-ARYL-2-TETRALONES | CORNING INC (US) | 2017-04-19 | — | — | EP | disclosed |
| EP-2467202-B1 | METHODS FOR SELECTIVELY SYNTHESIZING 1-ARYL-2-TETRALONES | CORNING INC (US) | 2017-04-19 | — | — | EP | disclosed |
| EP-2467202-A2 | METHODS FOR SELECTIVELY SYNTHESIZING 1-ARYL-2-TETRALONES | Corning Incorporated (US) | 2012-06-27 | — | — | EP | disclosed |
| EP-1955992-B1 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORP (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1955992-B1 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORP (JP) | 2011-11-23 | — | — | EP | disclosed |
| WO-2011022450-A2 | METHODS FOR SELECTIVELY SYNTHESIZING 1-ARYL-2-TETRALONES | CORNING INCORPORATED (US) | 2011-02-24 | — | — | WO | disclosed |
| WO-2011022450-A2 | METHODS FOR SELECTIVELY SYNTHESIZING 1-ARYL-2-TETRALONES | CORNING INCORPORATED (US) | 2011-02-24 | — | — | WO | disclosed |
| US-7829745-B1 | Methods for selectively synthesizing 1-aryl-2-tetralones | CORNING INCORPORATED (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829745-B1 | Methods for selectively synthesizing 1-aryl-2-tetralones | CORNING INCORPORATED (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829745-B1 | Methods for selectively synthesizing 1-aryl-2-tetralones | CORNING INCORPORATED (US) | 2010-11-09 | — | — | US | disclosed |
| US-7728154-B2 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7728154-B2 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7728154-B2 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20080200697-A1 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20080200697-A1 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20080200697-A1 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| EP-1955992-A2 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-13 | — | — | EP | disclosed |
| EP-1955992-A2 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200697-A1 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | SULT1E1, CYP2S1, SULT1A1 | GID4 4052/4885MAPT 4045/4885HPGD 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.