Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851192 | 0.81 | NFKB1 (0.39) | ALDH1A1GAANAAAMEN1KMT2A | |
| SCHEMBL8693432 | 0.81 | NFKB1 (0.39) | ALDH1A1GAANAAAMEN1KMT2A | |
| SCHEMBL19015180 | 0.81 | ALDH1A1 (0.56) | CPB1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL17438422 | 0.81 | ALDH1A1 (0.56) | CPB1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL17438421 | 0.81 | ALDH1A1 (0.56) | CPB1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL15748998 | 0.81 | ALDH1A1 (0.56) | CPB1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL4261378 | 0.80 | ALDH1A1 (0.58) | CPB1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL4083202 | 0.80 | ALDH1A1 (0.58) | CPB1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL4261374 | 0.80 | ALDH1A1 (0.58) | CPB1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL4361233 | 0.79 | ALDH1A1 (0.55) | CPB1ALDH1A1GAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | claimed |
| EP-0770083-B1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 2000-08-30 | — | — | EP | disclosed |
| EP-0682030-B1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| EP-0647644-B1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0770083-A1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| US-5618815-A | ANTIBACTERIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-08 | — | — | US | disclosed |
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| US-5508278-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| WO-1996001829-A1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-25 | — | — | WO | disclosed |
| EP-0684244-A1 | 1,9-bridged thiazolo(3,2-a)quinoline derivatives | BAYER AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| EP-0682030-A1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0647644-A1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |