Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.66 |
| ▸ | CCR2 | P41597 | 4/20 | 0.66 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.66 |
| ▸ | CCR7 | P32248 | 2/20 | 0.66 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209813 | 0.86 | CCR2 (0.66) | CCR5CCR2CXCR3CCR7 | |
| SCHEMBL1161322 | 0.80 | CCR5 (1.00) | CCR5CCR2CXCR3CCR7CXCR5 | |
| SCHEMBL30241629 | 0.80 | CCR5 (1.00) | CCR5CCR2CXCR3CCR7CXCR5 | |
| Hydrochloric Acid SCHEMBL29381708 | 0.79 | CCR5 (1.00) | CCR5CCR2CXCR3CCR7CXCR5 | |
| Hydrochloric Acid SCHEMBL48548 | 0.79 | CCR5 (1.00) | CCR5CCR2CXCR3CCR7CXCR5 | |
| Hydrochloric Acid SCHEMBL5208149 | 0.79 | CCR5 (0.98) | CCR5CCR2CXCR3CCR7CXCR5 | |
| Iodide SCHEMBL3031616 | 0.79 | CCR5 (1.00) | CCR5CCR2CXCR3CCR7CXCR5 | |
| Iodide SCHEMBL5212153 | 0.79 | CCR5 (1.00) | CCR5CCR2CXCR3CCR7CXCR5 | |
| Iodide SCHEMBL5211182 | 0.78 | CCR5 (0.76) | CCR5CCR2CXCR3CCR7CXCR5 | |
| Iodide SCHEMBL5204391 | 0.74 | CCR5 (1.00) | CCR5CCR2CXCR3CCR7CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166006-A | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-26 | — | — | US | disclosed |