Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.48 |
| ▸ | NQO2 | P16083 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097737 | 1.00 | FFAR1 (0.52) | FFAR1MTNR1AMTNR1BNQO2 | |
| SCHEMBL8088502 | 0.79 | HTR2A (0.56) | FFAR1MTNR1AMTNR1BNQO2 | |
| SCHEMBL8088503 | 0.79 | HTR2A (0.56) | FFAR1MTNR1AMTNR1BNQO2 | |
| SCHEMBL8102751 | 0.74 | HTR2C (0.60) | — | |
| SCHEMBL8102755 | 0.74 | HTR2C (0.60) | — | |
| SCHEMBL8333820 | 0.71 | FFAR1 (0.42) | FFAR1MTNR1AMTNR1B | |
| SCHEMBL8104735 | 0.71 | HTR2A (0.47) | FFAR1MTNR1AMTNR1B | |
| SCHEMBL8104739 | 0.71 | HTR2A (0.47) | FFAR1MTNR1AMTNR1B | |
| SCHEMBL8098166 | 0.71 | HTR2C (0.51) | MTNR1AMTNR1B | |
| SCHEMBL8098167 | 0.71 | HTR2C (0.51) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |