Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.52 |
| ▸ | NQO2 | P16083 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097742 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9019820 | 0.86 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9019823 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8101935 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL8088398 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8089386 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8089383 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8088400 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8101937 | 0.80 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8088983 | 0.79 | MTNR1B (0.52) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |