SCHEMBL8097769

SCHEMBL8097769

CC(C)(C)NC(=O)OC1CON(c2ccccc2C(F)(F)F)C1=O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 9/20 0.36
TDP1 Q9NUW8 8/20 0.36
RBP4 P02753 3/20 0.36
AKR1C3 P42330 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8097766 0.79 CYP1A2 (0.38) GAA
SCHEMBL8098688 0.73 L3MBTL1 (0.44) L3MBTL1TDP1AKR1C3ATM
SCHEMBL8105921 0.71 L3MBTL1 (0.44) L3MBTL1TDP1AKR1C3ATM
SCHEMBL8098668 0.71 L3MBTL1 (0.44) L3MBTL1TDP1AKR1C3ATM
SCHEMBL28719052 0.69 ACKR3 (0.35) L3MBTL1
SCHEMBL8106051 0.69 NOTUM (0.38) GAAL3MBTL1TDP1
SCHEMBL17332733 0.68 FFAR1 (0.38) GAA
SCHEMBL17332734 0.68 FFAR1 (0.38) GAA
SCHEMBL28720238 0.68 SMN1; SMN2 (0.40) TP53GAAL3MBTL1
SCHEMBL8099269 0.67 NOTUM (0.38) GAARBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed