Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088924 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL8088922 | 0.87 | MTNR1A (0.49) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL8089383 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL8089386 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL8088455 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL8088456 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL8104382 | 0.78 | MTNR1A (0.58) | MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL8101935 | 0.77 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL8098444 | 0.76 | MTNR1A (0.60) | MTNR1AMTNR1BCNR1CNR2 | |
| SCHEMBL8098442 | 0.76 | MTNR1A (0.60) | MTNR1AMTNR1BCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |