Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301136 | 0.74 | CYP3A4 (0.39) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL10439947 | 0.70 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL11658359 | 0.70 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL5838621 | 0.70 | TDP1 (0.39) | SLC6A3TRPA1CYP3A4TDP1 | |
| SCHEMBL6288582 | 0.69 | TAAR1 (0.50) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL10805698 | 0.69 | CYP3A4 (0.35) | SLC6A3TRPA1CYP3A4TDP1 | |
| SCHEMBL2452422 | 0.69 | SIGMAR1 (0.50) | ADRA2BADRA1AOPRK1SLC6A3KCNH2 | |
| SCHEMBL23075245 | 0.69 | RIPK1 (0.36) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL5716450 | 0.68 | SMN1; SMN2 (0.34) | TRPA1CYP3A4TDP1 | |
| SCHEMBL5716346 | 0.67 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732336-B1 | Process for the preparation of arylalkyl phosphines, arylalkyl phosphine oxides or arylalkyl phosphine sulfides | CYTEC CANADA INC (CA) | 2000-12-20 | — | — | EP | disclosed |
| EP-0732336-A1 | Process for the preparation of arylalkyl phosphines, arylalkyl phosphine oxides or arylalkyl phosphine sulfides | Cytec Canada Inc. (CA) | 1996-09-18 | — | — | EP | disclosed |
| US-5550295-A | Preparation of arylalkyl phosphines, phosphine oxides or phosphine sulfides | CYTEC TECHNOLOGY CORP. (US) | 1996-08-27 | — | — | US | disclosed |