SCHEMBL8097900

SCHEMBL8097900

CC(=O)OCC(C)N1C(=O)C=CC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.38
HPGD P15428 2/20 0.38
BLM P54132 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
WRN Q14191 1/20 0.38
HIF1A Q16665 1/20 0.38
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
NPSR1 Q6W5P4 2/20 0.33
HSP90AA1 P07900 1/20 0.33
HTT P42858 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
LMNA P02545 2/20 0.32
HSD17B10 Q99714 1/20 0.32
NLRP3 Q96P20 1/20 0.32
GAA P10253 1/20 0.32
P2RX4 Q99571 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8887670 0.82 ALDH1A1 (0.36) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL14878776 0.81 MAPT (0.44) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL15394161 0.80 MAPT (0.46) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL15694976 0.80 MAPT (0.46) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL15394427 0.80 MAPT (0.46) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL15394241 0.80 MAPT (0.46) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL8096047 0.79 ALDH1A1 (0.40) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL27459636 0.79 ALDH1A1 (0.36) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL5081930 0.78 MGLL (0.36) ALDH1A1HPGDBLMCYP1A2CYP2C19
SCHEMBL13178301 0.76 TDP1 (0.34) ALDH1A1TDP1LMNAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6165672-A Maleimide or alicyclic olefin-based monomers, copolymer resin of these monomers and photoresist using the resin HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2000-12-26 US claimed
CN-1125448-A 14-substituted marcfortines and derivatives useful as antiparasitic agents UPJOHN CO (US) 1996-06-26 CN claimed
US-6165672-A Maleimide or alicyclic olefin-based monomers, copolymer resin of these monomers and photoresist using the resin HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2000-12-26 US disclosed
CN-1125448-A 14-substituted marcfortines and derivatives useful as antiparasitic agents UPJOHN CO (US) 1996-06-26 CN disclosed