SCHEMBL8097972

SCHEMBL8097972

CC(C)(C)[Si](C)(Cl)CC1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
SIGMAR1 Q99720 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22769427 0.77 CYP1A2 (0.37) CYP1A2SIGMAR1
SCHEMBL7788561 0.77 CYP1A2 (0.37) CYP1A2SIGMAR1
SCHEMBL13599862 0.73 CYP1A2 (0.42) CYP1A2SIGMAR1
SCHEMBL10356856 0.73 CYP1A2 (0.42) CYP1A2SIGMAR1
SCHEMBL14523275 0.71 CYP1A2 (0.38) CYP1A2SIGMAR1
SCHEMBL13599865 0.71 CYP1A2 (0.40) CYP1A2SIGMAR1
SCHEMBL3895538 0.71 CYP1A2 (0.40) CYP1A2SIGMAR1
SCHEMBL1204274 0.71 CHRM5 (0.35) CYP1A2SIGMAR1
SCHEMBL13599863 0.71 CYP1A2 (0.40) CYP1A2SIGMAR1
SCHEMBL17750053 0.68 CYP1A2 (0.34) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156918-A Process for the preparation of silanes, with a tertiary hydrocarbon group in the a-position relative to the silicon atom WACKER-CHEMIE GMBH (DE) 2000-12-05 US disclosed