Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769427 | 0.84 | CYP1A2 (0.37) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL10356856 | 0.80 | CYP1A2 (0.42) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL13599862 | 0.80 | CYP1A2 (0.42) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL1204274 | 0.78 | CHRM5 (0.35) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL13599865 | 0.78 | CYP1A2 (0.40) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL3895538 | 0.78 | CYP1A2 (0.40) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL13599863 | 0.78 | CYP1A2 (0.40) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL8097972 | 0.77 | CYP1A2 (0.37) | CYP1A2SIGMAR1 | |
| SCHEMBL13599864 | 0.75 | CYP1A2 (0.36) | CYP1A2ACHECHRM5ADRA2CCHRM2 | |
| SCHEMBL5408352 | 0.75 | CYP1A2 (0.36) | CYP1A2ACHECHRM5ADRA2CCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980870-B1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | WACKER CHEMIE GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6156918-A | Process for the preparation of silanes, with a tertiary hydrocarbon group in the a-position relative to the silicon atom | WACKER-CHEMIE GMBH (DE) | 2000-12-05 | — | — | US | disclosed |
| CN-1245807-A | Preparation method of silicane whose alpha-position related to silicon atom possesses tertiary alkyl radical | WACKER CHEMIE GMBH (DE) | 2000-03-01 | — | — | CN | disclosed |
| EP-0980870-A1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | Wacker-Chemie GmbH (DE) | 2000-02-23 | — | — | EP | disclosed |