⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295237 | 0.89 | HTT (0.35) | — | |
| SCHEMBL209742 | 0.83 | — | — | |
| SCHEMBL9533249 | 0.82 | — | — | |
| SCHEMBL9847761 | 0.77 | CYP1A2 (0.35) | — | |
| SCHEMBL1306668 | 0.77 | L3MBTL1 (0.38) | — | |
| SCHEMBL1784012 | 0.77 | L3MBTL1 (0.41) | — | |
| SCHEMBL3952603 | 0.71 | DRD2 (0.39) | — | |
| SCHEMBL1069 | 0.71 | — | — | |
| SCHEMBL8629808 | 0.71 | — | — | |
| SCHEMBL151183 | 0.71 | CYP1A2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2406 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197888-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2024-06-20 | — | — | US | claimed |
| WO-2024114814-A1 | JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | ONQUALITY PHARMACEUTICALS CHINA LTD (CN) | 2024-06-06 | — | — | WO | claimed |
| US-20240174643-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2024-05-30 | — | — | US | claimed |
| WO-2024086296-A1 | COMPOUNDS USEFUL IN MODULATING EGFR AND PI3K | MEKANISTIC THERAPEUTICS LLC (US) | 2024-04-25 | — | — | WO | claimed |
| EP-4355741-A1 | SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2024-04-24 | — | — | EP | claimed |
| EP-3498716-B1 | SULFONYL BEARING THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATION AS ANTI-CANCER AGENT | UNIV XIAMEN (CN) | 2024-04-17 | — | — | EP | claimed |
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | claimed |
| US-11891388-B2 | Pyrazolopyridine compounds and uses thereof | INCYTE CORPORATION (US) | 2024-02-06 | — | — | US | claimed |
| US-20230310413-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING A MALT1 INHIBITOR AND A MIXTURE OF POLYETHYLENE GLYCOL WITH A FATTY ACID | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-05 | — | — | US | claimed |
| WO-2023165591-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | IMMUTHER PHARMATECH (SHANGHAI) CO., LTD. (CN) | 2023-09-07 | — | — | WO | claimed |
| US-4849320-A | Method of forming images | CIBA-GEIGY CORPORATION (US) | 1989-07-18 | — | — | US | claimed |
| US-4716162-A | BRAIN FUNCTION | SANKYO COMPANY, LIMITED (JP) | 1987-12-29 | — | — | US | claimed |
| US-4650868-A | 7-deazapurine derivatives useful as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-03-17 | — | — | US | claimed |
| US-4640929-A | Insecticidally, acaricidally, and nematocidally 2-amino-1,3-dithiane derivatives and pesticidal compositions therefor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-02-03 | — | — | US | claimed |
| EP-0111455-A2 | Unsaturated lactones | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | claimed |
| US-4393210-A | ANALGESIC, ANTIULCER, ANTIDEPRESSANT, ANTIHISTAMINE, ANTICHOLINERGIC | SEIYAKU CO., LTD. (JP) | 1983-07-12 | — | — | US | claimed |
| WO-1982000402-A1 | HERBICIDAL AND PLANT GROWTH REGULANT DIPHENYLPYRIDAZINONES | DIAMOND SHAMROCK CORP (US) | 1982-02-18 | — | — | WO | claimed |
| EP-0046069-A1 | Herbicidal and plant growth regulant diphenylpyridazinones | DIAMOND SHAMROCK CORPORATION (US) | 1982-02-17 | — | — | EP | claimed |
| US-3960858-A | 3-Hetero acyl-2,3-benzoxazepines | GRUPPO LEPETIT S.P.A. (IT) | 1976-06-01 | — | — | US | claimed |
| US-3937715-A | PLANT GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | claimed |