Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098230 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HSD17B1HSD11B1CA1 | |
| SCHEMBL7426652 | 0.92 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1CA1CA2CA9 | |
| SCHEMBL8083534 | 0.87 | CA12 (0.52) | SMN1; SMN2ALDH1A1HSD17B1HSD11B1CA1 | |
| SCHEMBL7433719 | 0.86 | F2 (0.43) | — | |
| SCHEMBL7433728 | 0.86 | F2 (0.43) | — | |
| SCHEMBL7442390 | 0.83 | CA1 (0.41) | SMN1; SMN2ALDH1A1CA1CA2CA9 | |
| SCHEMBL7443096 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1CA1CA2CA9 | |
| SCHEMBL7435478 | 0.80 | F2 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL7435474 | 0.80 | F2 (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL7438592 | 0.79 | F2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |