Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | FPR3 | P25089 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098230 | 0.87 | SMN1; SMN2 (0.43) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL8098083 | 0.87 | SMN1; SMN2 (0.43) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL8098018 | 0.86 | MTNR1A (0.51) | CA1CA2CA9ALDH1A1POLB | |
| SCHEMBL7426657 | 0.83 | HTT (0.43) | CA1CA2CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL2678930 | 0.82 | KMT2A (0.72) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL7426652 | 0.82 | ALDH1A1 (0.43) | CA1CA2CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL8089921 | 0.82 | MMP8 (0.48) | CA12CA2CA9KMT2AMEN1 | |
| SCHEMBL8090095 | 0.82 | KDM4E (0.44) | SMN1; SMN2MAPT | |
| SCHEMBL8091445 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1FPR3L3MBTL1 | |
| SCHEMBL8083610 | 0.77 | MMP8 (0.54) | KMT2AEPHX1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | claimed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |