Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211051 | 0.82 | CYP2C19 (0.41) | CYP2C19CYP2D6OPRM1LMNAPOLB | |
| SCHEMBL200228 | 0.81 | CYP2C19 (0.40) | CYP2C19CYP2D6OPRM1LMNAPOLB | |
| SCHEMBL32688968 | 0.79 | CYP2D6 (0.42) | CYP2C19CYP2D6OPRM1LMNAPOLB | |
| SCHEMBL27619841 | 0.78 | CYP2D6 (0.38) | CYP2C19CYP2D6OPRM1LMNAPOLB | |
| SCHEMBL11703278 | 0.77 | CYP2D6 (0.37) | CYP2C19CYP2D6OPRM1LMNAADAM17 | |
| SCHEMBL11703272 | 0.77 | CYP2D6 (0.37) | CYP2C19CYP2D6OPRM1LMNAADAM17 | |
| SCHEMBL25428359 | 0.76 | CYP2D6 (0.36) | CYP2C19CYP2D6OPRM1LMNASLC22A1 | |
| SCHEMBL5838108 | 0.76 | CYP2D6 (0.36) | CYP2C19CYP2D6OPRM1LMNAADAM17 | |
| SCHEMBL5837506 | 0.76 | CYP2D6 (0.36) | CYP2C19CYP2D6OPRM1LMNAADAM17 | |
| SCHEMBL1141594 | 0.76 | CYP2D6 (0.36) | CYP2C19CYP2D6OPRM1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165672-A | Maleimide or alicyclic olefin-based monomers, copolymer resin of these monomers and photoresist using the resin | HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) | 2000-12-26 | — | — | US | disclosed |