SCHEMBL25428359

SCHEMBL25428359

C1=CC2CCC1C2.CCOC(=O)C1(C)CC2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
P2RX7 Q99572 1/20 0.34
F10 P00742 2/20 0.34
CETP P11597 1/20 0.33
SLC22A1 O15245 1/20 0.31
OPRM1 P35372 1/20 0.31
HTR2C P28335 3/20 0.30
HTR2B P41595 3/20 0.30
PTPN2 P17706 1/20 0.30
PTPN1 P18031 1/20 0.30
CDC25B P30305 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
TMIGD3 P0DMS9 1/20 0.30
ADORA2A P29274 1/20 0.30
TSPO P30536 1/20 0.30
ADORA1 P30542 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200228 0.94 CYP2C19 (0.40) CYP2D6CYP2C19P2RX7F10CETP
SCHEMBL201163 0.82 CYP2D6 (0.38) CYP2D6CYP2C19P2RX7CETPHTR2C
SCHEMBL200578 0.80 CYP2C19 (0.36) CYP2D6CYP2C19P2RX7CETPLMNA
SCHEMBL21593923 0.79 P2RX7 (0.36) CYP2D6CYP2C19P2RX7CETP
SCHEMBL14628487 0.79 P2RX7 (0.36) CYP2D6CYP2C19P2RX7CETP
SCHEMBL4253408 0.79 P2RX7 (0.36) CYP2D6CYP2C19P2RX7CETP
SCHEMBL32689139 0.79 EPHX2 (0.38) CYP2D6CYP2C19P2RX7LMNA
SCHEMBL5347783 0.78 P2RX7 (0.35) CYP2D6CYP2C19P2RX7CETP
SCHEMBL21593883 0.78 CETP (0.35) CYP2D6CYP2C19P2RX7CETP
SCHEMBL1451060 0.78 CETP (0.37) CYP2D6CYP2C19P2RX7CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132366-A1 CYCLOPENTENE RECOVERY METHOD 日本ゼオン株式会社 2023-07-13 WO disclosed