Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 12/20 | 0.42 |
| ▸ | FNTB | P49356 | 12/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446560 | 0.85 | FNTA (0.45) | CCR5CCR2FNTAFNTBPGGT1B | |
| SCHEMBL8102468 | 0.85 | KDM4E (0.44) | KDM4EFNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8431156 | 0.85 | FNTA (0.47) | FNTAFNTBPGGT1BKCNH2PKM | |
| SCHEMBL8098304 | 0.85 | FNTA (0.47) | FNTAFNTBPGGT1BKCNH2PKM | |
| SCHEMBL8095468 | 0.82 | FNTA (0.43) | CCR5CCR2FNTAFNTBPGGT1B | |
| SCHEMBL8097399 | 0.81 | GPR119 (0.43) | FNTAFNTBPGGT1BKCNH2KMT2A | |
| SCHEMBL8095385 | 0.81 | FNTA (0.46) | CCR5CCR2FNTAFNTBPGGT1B | |
| SCHEMBL8097456 | 0.80 | FNTA (0.44) | CCR5FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8095888 | 0.80 | FNTA (0.42) | CCR5CCR2FNTAFNTBPGGT1B | |
| SCHEMBL8101380 | 0.80 | FNTA (0.43) | CCR5CCR2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |