Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | FNTA | P49354 | 12/20 | 0.41 |
| ▸ | FNTB | P49356 | 12/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 11/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088808 | 0.85 | CYP11B1 (0.44) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8534856 | 0.83 | CYP11B1 (0.49) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8097403 | 0.83 | CYP11B1 (0.49) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8098299 | 0.81 | CCR5 (0.44) | KMT2ACYP11B1CYP11B2FNTAFNTB | |
| SCHEMBL8102468 | 0.79 | KDM4E (0.44) | MEN1ALDH1A1KMT2AFNTAFNTB | |
| SCHEMBL8088813 | 0.78 | CYP11B1 (0.52) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8531991 | 0.78 | CYP11B1 (0.52) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL8097401 | 0.75 | GPR119 (0.43) | GPR119MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8088396 | 0.72 | FNTA (0.45) | ALDH1A1CYP11B1CYP11B2FNTAFNTB | |
| SCHEMBL8103720 | 0.71 | FNTA (0.46) | CYP11B1CYP11B2FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |