Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14955457 | 0.84 | TRPV4 (0.55) | SMN1; SMN2ALDH1A1HPGDGAAMAPT | |
| SCHEMBL696485 | 0.82 | IDH1 (0.62) | SMN1; SMN2ALDH1A1HPGDGAAMAPT | |
| SCHEMBL11305074 | 0.81 | TRPV4 (0.53) | SMN1; SMN2ALDH1A1HPGDGAAMAPT | |
| SCHEMBL333191 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL6464917 | 0.75 | KDM4E (0.60) | ALDH1A1HPGDGAAMAPTMEN1 | |
| SCHEMBL7565660 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HPGDGAAMAPT | |
| SCHEMBL27993813 | 0.73 | RXFP1 (0.55) | SMN1; SMN2ALDH1A1HPGDGAAMAPT | |
| SCHEMBL6434867 | 0.73 | RXFP1 (0.61) | SMN1; SMN2CYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL11121506 | 0.73 | HDAC3 (0.54) | SMN1; SMN2ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL9584096 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| CN-1039492-C | Herbicides | ZENECA LTD (GB) | 1998-08-12 | — | — | CN | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| CN-1095066-A | Weedicide | ZENECA LTD (GB) | 1994-11-16 | — | — | CN | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |