SCHEMBL7565660

SCHEMBL7565660

CCOC(=O)Nc1cccc(C(F)(F)F)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.62
MAPT P10636 5/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
LMNA P02545 2/20 0.61
GAA P10253 2/20 0.61
MAPK1 P28482 1/20 0.61
HSD17B10 Q99714 1/20 0.61
XBP1 P17861 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
TP53 P04637 1/20 0.58
ALDH1A1 P00352 5/20 0.58
HTT P42858 1/20 0.57
RAB9A P51151 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
HPGD P15428 1/20 0.56
CYP1A2 P05177 1/20 0.55
POLB P06746 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C9 P11712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064159 0.87 ALDH1A1 (0.65) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL13154805 0.87 MAPK1 (0.62) SMN1; SMN2MAPTLMNAMAPK1HSD17B10
SCHEMBL596433 0.86 ALDH1A1 (0.60) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL2094340 0.85 MAPT (0.61) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL8300400 0.85 SMN1; SMN2 (0.52) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL333191 0.85 SMN1; SMN2 (0.65) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL515008 0.84 SMN1; SMN2 (0.68) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL7565149 0.84 MAPK1 (0.81) SMN1; SMN2MAPTLMNAMAPK1HSD17B10
SCHEMBL3372960 0.83 SMN1; SMN2 (0.56) SMN1; SMN2MAPTMEN1KMT2ALMNA
SCHEMBL12327612 0.83 ALDH1A1 (0.58) SMN1; SMN2MAPTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276541-B2 Use of hydroxyl-functional polyalkylorganosiloxanes as solvents for cationic photoinitiators for use in radiation- curable silicones GOLDSCHMIDT AG (DE) 2007-10-02 US disclosed
US-20020146633-A1 FLUORINATED AROMATIC ACETAL POLYMERS AND PHOTOSENSITIVE COMPOSITIONS CONTAINING SUCH POLYMERS KODAK POLYCHROME GRAPHICS L.L.C. 2002-10-10 US disclosed
US-6458503-B1 BLEND WITH DIAZO RESIN; LITHOGRAPHIC PRINTING PLATES; PHOTOPOLYMERIZATION AND CROSSLINKING KODAK POLYCHROME GRAPHICS LLC 2002-10-01 US disclosed
WO-2002073315-A1 FLUORINATED AROMATIC ACETAL POLYMERS AND PHOTOSENSITIVE COMPOSITIONS CONTAINING SUCH POLYMERS KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 2002-09-19 WO disclosed
US-5911911-A Polymerized liquid-crystalline compositions BASF AKTIENGESELLSCHAFT (DE) 1999-06-15 US disclosed