Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108131 | 0.83 | SLC6A4 (0.47) | CREBBPCA12CA9CA2ALDH1A1 | |
| SCHEMBL7864965 | 0.73 | OPRL1 (0.49) | ALDH1A1HTR6MEN1TSHRKMT2A | |
| SCHEMBL4014689 | 0.73 | OPRL1 (0.49) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL31742261 | 0.71 | CA12 (0.44) | CREBBPCA12CA9CA2ALDH1A1 | |
| SCHEMBL3966205 | 0.71 | CA12 (0.44) | CREBBPCA12CA9CA2ALDH1A1 | |
| SCHEMBL10291046 | 0.68 | CA12 (0.55) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL28059442 | 0.68 | CA12 (0.55) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL3563271 | 0.66 | CA12 (0.56) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL28228343 | 0.66 | CA12 (0.56) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL7866465 | 0.66 | PIK3CA (0.45) | CREBBPCA12CA9CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107307-A | PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0969005-A1 | Azabicyclic inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |