SCHEMBL8098495

SCHEMBL8098495

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)CCCNc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
MAPT P10636 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.40
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
KCNH3 Q9ULD8 3/20 0.33
PTPN1 P18031 1/20 0.33
PTPRZ1 P23471 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C19 P33261 2/20 0.32
PPARG P37231 1/20 0.32
DRD4 P21917 2/20 0.31
HTR7 P34969 1/20 0.31
ACHE P22303 1/20 0.31
LMNA P02545 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10507363 0.78 ALDH1A1 (0.43) ALDH1A1MAPTL3MBTL1HDAC3HDAC1
SCHEMBL2561565 0.73 NPC1 (0.51) HDAC3HDAC1HDAC2LMNA
SCHEMBL2065279 0.73 ALDH1A1 (1.00) ALDH1A1MAPTL3MBTL1HDAC3HDAC1
SCHEMBL4970157 0.73 ALDH1A1 (0.89) ALDH1A1MAPTL3MBTL1HDAC3HDAC1
SCHEMBL17501646 0.73 ALDH1A1 (0.46) ALDH1A1MAPTL3MBTL1HDAC3HDAC1
SCHEMBL3625694 0.72 ALDH1A1 (0.52) ALDH1A1MAPTL3MBTL1HDAC3HDAC1
SCHEMBL8094692 0.72 CA3 (0.31)
SCHEMBL11759173 0.71 ALDH1A1 (0.84) ALDH1A1MAPTL3MBTL1HDAC3HDAC1
Hydrochloric Acid SCHEMBL3634998 0.71 ALDH1A1 (0.94) ALDH1A1MAPTL3MBTL1HDAC3HDAC1
SCHEMBL14968385 0.71 ALDH1A1 (0.84) ALDH1A1MAPTL3MBTL1HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6054615-A Fluorinated quaternary ammonium salts E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-04-25 US disclosed