SCHEMBL8098529

SCHEMBL8098529

N#CC(O)C1=CC=CCC1=S

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6960032 0.81
SCHEMBL4456499 0.77
SCHEMBL1305504 0.73
SCHEMBL18321015 0.72
SCHEMBL11884208 0.70
SCHEMBL1706676 0.68
SCHEMBL7978329 0.68 MAOB (0.34)
SCHEMBL7138699 0.67 GABBR2 (0.32)
SCHEMBL4446823 0.67 GABBR2 (0.32)
SCHEMBL5846242 0.67 PTGS1 (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0666320-B1 Process for producing alpha-hydroxy acid or alpha-hydroxyamide by microorganisms MITSUBISHI RAYON CO (JP) 2000-12-20 EP disclosed
US-5756306-A HYDROLYSIS OF COMPOUNDS USING MICROORGAMISMS TO FORM ALPHA HYDROXY ACIDS OR AMIDES NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1998-05-26 US disclosed
EP-0773297-A2 Process for producing alfa-hydroxy acid or alfa-hydroxyamide by microorganism NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1997-05-14 EP disclosed
US-5508181-A REACTING AN ALPHA-HYDROXYNITRILE (OR MIXTURE WITH AN ALDEHYDE) WITH HYDROGEN CYANIDE IN PRESENCE OF PHOSPHITE OR HYPOPHOSPHITE IONS NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1996-04-16 US disclosed
EP-0666320-A2 Process for producing alpha-hydroxy acid or alpha-hydroxyamide by microorganisms NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1995-08-09 EP disclosed