Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24740469 | 0.69 | FBP1 (0.47) | FBP1HDAC2ALDH1A1LMNAMAPT | |
| SCHEMBL8098529 | 0.68 | TSHR (0.31) | — | |
| SCHEMBL9412021 | 0.65 | PGR (0.48) | FBP1HDAC2ALDH1A1LMNAMAPT | |
| SCHEMBL9412024 | 0.65 | PGR (0.48) | FBP1HDAC2ALDH1A1LMNAMAPT | |
| SCHEMBL10147242 | 0.65 | FBP1 (0.47) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL6960032 | 0.65 | — | — | |
| SCHEMBL7978333 | 0.63 | ALDH1A1 (0.39) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL14046550 | 0.63 | FBP1 (0.44) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL1687898 | 0.62 | FBP1 (0.59) | FBP1HDAC2ALDH1A1LMNAMAPT | |
| SCHEMBL21574805 | 0.62 | FBP1 (0.59) | FBP1HDAC2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239280-B1 | OXIDATION THE CORRESPONSING THIOIMIDAZOLE COMPOUND | MERCK & CO., INC. | 2001-05-29 | — | — | US | disclosed |