SCHEMBL809871

SCHEMBL809871

C=Cc1cc(OC)c(CCl)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.37
TTR P02766 1/20 0.35
ACHE P22303 2/20 0.33
MAPT P10636 2/20 0.33
NQO1 P15559 1/20 0.33
LMNA P02545 1/20 0.33
MITF O75030 1/20 0.33
ABCB1 P08183 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MCL1 Q07820 1/20 0.33
TRPA1 O75762 1/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
IMPDH2 P12268 1/20 0.33
IMPDH1 P20839 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809812 0.87 NQO1 (0.45) L3MBTL1TTRMAPTNQO1ALDH1A1
SCHEMBL809666 0.85 ALDH1A1 (0.38) L3MBTL1MAPTLMNAALDH1A1MCL1
SCHEMBL810209 0.81 HTT (0.40) MAPTLMNAABCB1ALDH1A1KDM4E
SCHEMBL809738 0.81 GAA (0.40) L3MBTL1MAPTALDH1A1GAA
SCHEMBL3972598 0.80 L3MBTL1 (0.44) L3MBTL1TTRMAPTNQO1LMNA
SCHEMBL810363 0.79 L3MBTL1 (0.40) L3MBTL1ALDH1A1
SCHEMBL809803 0.77 ALDH1A1 (0.44) L3MBTL1ALDH1A1
SCHEMBL810260 0.77 L3MBTL1 (0.41) L3MBTL1ALDH1A1
SCHEMBL809642 0.76 L3MBTL1 (0.38) L3MBTL1ALDH1A1
SCHEMBL810180 0.76 L3MBTL1 (0.40) L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012015977-A3 HIGHLY PORTABLE AND STABLE WORK STATION HERSCHLER MATTHEW B (US) 2012-05-10 WO disclosed
EP-2192645-B1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORP (JP) 2011-11-30 EP disclosed
US-20110250525-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORPORATION (JP) 2011-10-13 US disclosed
EP-2192645-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2010-06-02 EP disclosed