Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115393 | 0.81 | MAOB (0.40) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL7115666 | 0.75 | GAA (0.44) | KMT2AMEN1KDM4ECYP19A1MAPT | |
| SCHEMBL7115046 | 0.74 | ABCG2 (0.52) | KDM4EALDH1A1HSD17B10HPGDCYP3A4 | |
| SCHEMBL4098612 | 0.72 | HPGD (0.39) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL7108704 | 0.72 | MAOA (0.46) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL7115413 | 0.70 | CYP19A1 (0.39) | KMT2AMEN1KDM4ECYP19A1MAPT | |
| SCHEMBL7110728 | 0.69 | PTGS2 (0.43) | KMT2AMEN1KDM4ECYP2D6MAPT | |
| SCHEMBL5758407 | 0.67 | MAOB (0.53) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL9353238 | 0.66 | CYP3A4 (0.46) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL7115723 | 0.66 | ABCG2 (0.53) | KDM4ECYP19A1MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000044568-A | INTERMEDIATE FOR DIBENZOXEPIN AND DIBENZOTHIEPINE DERIVATIVES HAVING PHYSIOLOGICAL ACTION | NIPPON SUISAN KAISHA LTD | 2000-02-15 | — | — | JP | disclosed |