Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18517054 | 0.88 | GAA (0.60) | GAAABCG2ABCB1ABCC1ALDH1A1 | |
| SCHEMBL9191296 | 0.86 | GAA (0.64) | GAACA12CA1CA9ALDH1A1 | |
| SCHEMBL9319431 | 0.84 | GAA (0.62) | GAAALDH1A1FFAR1PPARGPPARD | |
| SCHEMBL5605404 | 0.82 | ALDH1A1 (0.44) | GAACA12CA1CA9ALDH1A1 | |
| SCHEMBL30561156 | 0.82 | ALDH1A1 (0.44) | GAACA12CA1CA9ALDH1A1 | |
| SCHEMBL13510740 | 0.82 | GAA (0.59) | GAACA12CA1CA9ALDH1A1 | |
| SCHEMBL13510776 | 0.82 | GAA (0.38) | GAAABCG2ABCB1ABCC1CA12 | |
| SCHEMBL9319774 | 0.80 | GAA (0.48) | GAA | |
| SCHEMBL17009073 | 0.79 | GAA (0.47) | GAAABCG2ABCB1ABCC1ALDH1A1 | |
| SCHEMBL8705954 | 0.78 | ESR1 (0.47) | GAAALDH1A1ALDH2GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591102-B1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| US-5428162-A | For protecting organic materials against thermal, oxidative or light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| US-5412088-A | 6-O-substituted guanosine derivatives | RUTGERS, THE STATE UNIVERSITY (US) | 1995-05-02 | — | — | US | disclosed |
| US-5407658-A | Analogs of cytochalasin B as radiopharmaceuticals for nuclear imaging of trans-membrane glucose transport | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-18 | — | — | US | disclosed |
| WO-1994028943-A1 | ANALOGS OF CYTOCHALASIN B AS RADIOPHARMACEUTICALS FOR NUCLEAR IMAGING OF TRANS-MEMBRANE GLUCOSE TRANSPORT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-22 | — | — | WO | disclosed |
| US-5342926-A | Analogs of cytochalasin B as radiopharmaceuticals for nuclear imaging of trans-membrane glucose transport | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-08-30 | — | — | US | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |