SCHEMBL5605404

SCHEMBL5605404

O=C1Oc2ccccc2C1c1ccc(OCCO)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
RECQL P46063 1/20 0.44
GAA P10253 2/20 0.42
KCNA3 P22001 1/20 0.42
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
GPR174 Q9BXC1 1/20 0.40
MAPK1 P28482 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
CYP2C9 P11712 1/20 0.36
ALDH2 P05091 1/20 0.36
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30561156 1.00 ALDH1A1 (0.44) ALDH1A1RECQLGAAKCNA3MAPT
SCHEMBL3261989 0.84 LMNA (0.46) GAAKCNA3LMNAGPR174MEN1
SCHEMBL29612322 0.83 MAPT (0.49) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL9280351 0.83 ALOX15 (0.49) ALDH1A1GAAMAPTLMNAHTT
SCHEMBL8098842 0.82 GAA (0.60) ALDH1A1GAAMAPTCA12CA1
SCHEMBL8100448 0.81 CYP2C9 (0.38) ALDH1A1RECQLGAAHTTMAPK1
SCHEMBL7759240 0.77 CYP3A4 (0.36) ALDH1A1RECQLGAAGPR174CA12
SCHEMBL8101288 0.77 GAA (0.49) ALDH1A1GAAMAPTLMNAMEN1
SCHEMBL29880960 0.76 GAA (0.50) ALDH1A1GAAMAPTMAPK1MEN1
SCHEMBL8100817 0.76 GAA (0.50) ALDH1A1GAAMAPTMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405519-A1 ADDITIVE MIXTURE FOR STABILIZATION OF POLYOL AND POLYURETHANE BASF SE (DE) 2018-11-28 EP disclosed
WO-2017125291-A1 ADDITIVE MIXTURE FOR STABILIZATION OF POLYOL AND POLYURETHANE BASF SE (DE) 2017-07-27 WO disclosed
US-20070072979-A1 Dispersing agents in nanocomposites POLYMERS AUSTRALIA PTY, LIMITED (AU) 2007-03-29 US disclosed
EP-0591102-B1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA SC HOLDING AG (CH) 2000-10-18 EP disclosed
CN-1040208-C 3-(2-acyloxyethoxyphenyl) benzofuran-2-ones for use as stabilizers SPECIALTY CHEMICALS HOLDING IN (CH) 1998-10-14 CN disclosed
US-5428162-A For protecting organic materials against thermal, oxidative or light-induced degradation CIBA-GEIGY CORPORATION (US) 1995-06-27 US disclosed
EP-0591102-A1 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers CIBA-GEIGY AG (CH) 1994-04-06 EP disclosed