Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28524123 | 1.00 | DNM1 (0.52) | DNM1HTTSLC22A1PLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL28241165 | 1.00 | DNM1 (0.52) | DNM1HTTSLC22A1PLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL6832620 | 1.00 | DNM1 (0.52) | DNM1HTTSLC22A1PLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL2997677 | 1.00 | DNM1 (0.52) | DNM1HTTSLC22A1PLA2G1BHSP90AA1 | |
| SCHEMBL10624369 | 0.98 | DNM1 (0.50) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| SCHEMBL5968976 | 0.98 | DNM1 (0.50) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| SCHEMBL7773358 | 0.98 | DNM1 (0.50) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| Bromide SCHEMBL28721739 | 0.95 | DNM1 (0.52) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| Bromide SCHEMBL18938572 | 0.95 | DNM1 (0.52) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| Bromide SCHEMBL28721758 | 0.93 | DNM1 (0.54) | DNM1HTTSLC22A1HSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842603-B1 | Agricultural chemical composition | KAO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| EP-0638236-B1 | Agricultural chemical composition | KAO CORP (JP) | 1998-09-30 | — | — | EP | disclosed |
| EP-0842603-A1 | Agricultural chemical composition | KAO CORPORATION (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0638236-A1 | Agricultural chemical composition | KAO CORPORATION (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-4724098-A | THIXOTROPIC AGENTS FOR COATINGS AND ANTI-RUST PRIMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-09 | — | — | US | disclosed |
| US-4073735-A | DISCOLORATION INHIBITION, ALKALI METAL SILICATE | COLGATE PALMOLIVE COMPANY (US) | 1978-02-14 | — | — | US | disclosed |