Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.88 |
| ▸ | EGFR | P00533 | 6/20 | 0.82 |
| ▸ | ABL1 | P00519 | 5/20 | 0.82 |
| ▸ | ABL2 | P42684 | 5/20 | 0.82 |
| ▸ | RIPK2 | O43353 | 8/20 | 0.78 |
| ▸ | LCK | P06239 | 3/20 | 0.77 |
| ▸ | TEK | Q02763 | 2/20 | 0.77 |
| ▸ | KDR | P35968 | 1/20 | 0.64 |
| ▸ | FGR | P09769 | 1/20 | 0.63 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.63 |
| ▸ | TXK | P42681 | 1/20 | 0.63 |
| ▸ | FRK | P42685 | 1/20 | 0.63 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8114119 | 0.93 | SRC (0.98) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL8098925 | 0.88 | SRC (0.89) | SRCEGFRABL1ABL2LCK | |
| SCHEMBL6465227 | 0.87 | SRC (1.00) | SRCEGFRABL1LCKTEK | |
| Hydrochloric Acid SCHEMBL6465660 | 0.86 | SRC (0.98) | SRCEGFRABL1LCKTEK | |
| SCHEMBL7020106 | 0.85 | SRC (0.87) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL13020337 | 0.85 | SRC (0.72) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL27397203 | 0.84 | SRC (0.67) | SRCEGFRABL1ABL2RIPK2 | |
| Hydrochloric Acid SCHEMBL7098308 | 0.84 | SRC (0.85) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL7019630 | 0.83 | SRC (0.81) | SRCEGFRABL1ABL2RIPK2 | |
| SCHEMBL16752225 | 0.82 | SRC (0.89) | SRCEGFRABL1LCKTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051577-A | TYROSINE INHIBITORS; BONE DISORDERS | NOVARTIS AG (CH) | 2000-04-18 | — | — | US | disclosed |