Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.72 |
| ▸ | LCK | P06239 | 3/20 | 0.72 |
| ▸ | TEK | Q02763 | 2/20 | 0.72 |
| ▸ | EGFR | P00533 | 9/20 | 0.69 |
| ▸ | ABL1 | P00519 | 7/20 | 0.69 |
| ▸ | ABL2 | P42684 | 7/20 | 0.69 |
| ▸ | FGR | P09769 | 1/20 | 0.67 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.67 |
| ▸ | TXK | P42681 | 1/20 | 0.67 |
| ▸ | FRK | P42685 | 1/20 | 0.67 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.67 |
| ▸ | RIPK2 | O43353 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RGS12 | O14924 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13020005 | 0.89 | SRC (0.78) | SRCLCKTEKEGFRABL1 | |
| SCHEMBL7020106 | 0.88 | SRC (0.87) | SRCLCKTEKEGFRABL1 | |
| Hydrochloric Acid SCHEMBL7098308 | 0.87 | SRC (0.85) | SRCLCKTEKEGFRABL1 | |
| SCHEMBL8098939 | 0.85 | SRC (0.88) | SRCLCKTEKEGFRABL1 | |
| SCHEMBL6465227 | 0.84 | SRC (1.00) | SRCLCKTEKEGFRABL1 | |
| Hydrochloric Acid SCHEMBL6465660 | 0.83 | SRC (0.98) | SRCLCKTEKEGFRABL1 | |
| SCHEMBL7019904 | 0.82 | SRC (1.00) | SRCLCKTEKEGFRABL1 | |
| SCHEMBL8114105 | 0.81 | SRC (1.00) | SRCLCKTEKEGFRABL1 | |
| SCHEMBL20351628 | 0.81 | SRC (0.80) | SRCLCKTEKEGFRABL1 | |
| Hydrochloric Acid SCHEMBL8107815 | 0.81 | SRC (0.98) | SRCLCKTEKEGFRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2009062118-A2 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | RAB1A, COPB1, GOLT1B | SRC 1332/4885LCK 1980/4885TEK 4347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.