Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637137 | 1.00 | KDM4E (0.56) | KDM4EKMT2AMEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8580878 | 0.99 | KDM4E (0.55) | KDM4EKMT2AMEN1NPC1RAB9A | |
| Cadaverine Tartrate SCHEMBL27494138 | 0.93 | KDM4E (0.50) | KDM4EKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6627628 | 0.85 | KDM4E (0.64) | KDM4EKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3718479 | 0.85 | KDM4E (0.64) | KDM4EKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14222023 | 0.84 | OPRM1 (0.45) | KDM4EKMT2AMEN1NPC1RAB9A | |
| SCHEMBL962133 | 0.84 | OPRM1 (0.62) | KDM4EKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14074899 | 0.84 | KDM4E (0.62) | KDM4EKMT2AMEN1NPC1RAB9A | |
| SCHEMBL1760955 | 0.83 | ALDH1A1 (0.46) | KDM4EKMT2AMEN1LMNAPOLB | |
| SCHEMBL7964628 | 0.82 | SLC6A2 (0.58) | KDM4ESLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929243-A | STEREOSPECIFIC HYDROLYSIS OF AN N-PROTECTED ETHYL ESTER OF 2-BENZYL-2-CARBETHOXY-3-AMINO PROPIONIATE USING AN ESTERASE AND OBTAINING AN OPTICAL STEREOISOMER OF THE CORRESPONDING MONO-ACID; DEPROTECTING; CYCLIZATION; CHEMICAL REDUCTION | MERCK & CO., INC. (US) | 1999-07-27 | — | — | US | disclosed |
| US-5929243-A | STEREOSPECIFIC HYDROLYSIS OF AN N-PROTECTED ETHYL ESTER OF 2-BENZYL-2-CARBETHOXY-3-AMINO PROPIONIATE USING AN ESTERASE AND OBTAINING AN OPTICAL STEREOISOMER OF THE CORRESPONDING MONO-ACID; DEPROTECTING; CYCLIZATION; CHEMICAL REDUCTION | MERCK & CO., INC. (US) | 1999-07-27 | — | — | US | disclosed |
| WO-1997036873-A1 | PIPERIDINES, PYRROLIDINES AND HEXAHYDRO-1H-AZEPINES PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |