SCHEMBL8099008

SCHEMBL8099008

COCc1cc(O)ccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 1/20 0.44
PRKCE Q02156 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
MYLK Q15746 2/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
RECQL P46063 2/20 0.42
KMT2A Q03164 2/20 0.42
PRKCG P05129 1/20 0.42
PRKCA P17252 1/20 0.42
APEX1 P27695 1/20 0.42
TYR P14679 5/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CYP3A4 P08684 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8393208 0.86 TYR (0.36) HSD17B3ALDH1A1TYRCA12CA1
SCHEMBL29017772 0.83 HSD17B3 (0.44) HSD17B3PRKCEALDH1A1TDP1MYLK
SCHEMBL19899827 0.81 MAPT (0.44) PRKCEALDH1A1TDP1MYLKMEN1
SCHEMBL29354986 0.81 MAPT (0.44) PRKCEALDH1A1TDP1MYLKMEN1
SCHEMBL10883526 0.81 ALDH1A1 (0.48) PRKCEALDH1A1TDP1MYLKMEN1
SCHEMBL108757 0.81 MAPT (0.44) PRKCEALDH1A1TDP1MYLKMEN1
SCHEMBL28379905 0.80 HSD17B3 (0.47) HSD17B3PRKCEALDH1A1TDP1MYLK
Hydrochloric Acid SCHEMBL6256039 0.79 MAPT (0.42) PRKCEALDH1A1TDP1MYLKMEN1
Hydrochloric Acid SCHEMBL7132484 0.79 MAPT (0.42) PRKCEALDH1A1TDP1MYLKMEN1
Bromide SCHEMBL26108834 0.79 MAPT (0.42) PRKCEALDH1A1TDP1MYLKMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667143-B1 Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol OREAL (FR) 1996-10-09 EP claimed
EP-0667143-A1 Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol L'OREAL (FR) 1995-08-16 EP claimed
WO-2014202150-A1 NEW CATIONIC DYES, KITS AND COMPOSITIONS THEREOF, AND PROCESS FOR DYEING KERATIN FIBERS ALFA PARF GROUP S.P.A. (IT) 2014-12-24 WO disclosed
US-6022382-A Processes and kits for dyeing keratinous fibers with a para-phenylenediamine containing a primary, secondary or tertiary amine function, a meta-phenylenediamine, and a para-aminophenol or a meta-aminophenol L'OREAL (FR) 2000-02-08 US disclosed
US-5863300-A HAIR DYES L'OREAL (FR) 1999-01-26 US disclosed
EP-0667143-B1 Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol OREAL (FR) 1996-10-09 EP disclosed
EP-0667143-A1 Keratinous fiber oxidation dyeing composition containing a paraphenylenediamine, a metaphenylenediamine and a paraaminophenol or a metaaminophenol L'OREAL (FR) 1995-08-16 EP disclosed